A study conducted by the Institute of Cancer Research has found the first genes linked to testicular cancer. The genes of 730 men, who had at some time developed testicular cancer, were compared with those of healthy men. Most of the men who suffered from testicular cancer shared common DNA variants on chromosomes 5, 6 and 12, that weren’t present in the other men.
It has been known for some time that there was an hereditary aspect of the gene, but this is the first time that a gene has been pinpointed. The study found that men possessing these genes can be at a significantly higher risk of developing testicular cancer than men who don’t. Men who inherit the strongest of the three genes can be up to 3 times as likely to fall victim to testicular cancer. Men who have inherited all three of the DNA variants can be up to four times more likely to develop testicular cancer.
Researchers believe there are still more genetic risk factors related to testicular cancer. With the knowledge gained from this study, scientists are one step closer to being able to identify men of high risk factors, possibly leading to early detection or prevention.
Full article available from:
http://www.medicalnewstoday.com/articles/152190.php
By Melanie Johnston- 42001436
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